I: The major histocompatibility complex (MHC) of the water vole - SimMasto.org

The major histocompatibility complex (MHC) of the water vole
keys to understanding the mechanism of selection

Information is provided about the current state of knowledge on the MHC selection
in the water Vole.

   - The slide-show (39 slides) reviews the MHC selection mechanisms at various time
     scales (contemporary, historical) as they are known in voles. Some detection methods
     are also overviewed.

   - four articles addressing focus aspects of the MHC selection are made available :

           . Bryja et al., 2006: Duplication, balancing selection and trans-species evolution
             explain the high levels of polymorphism of the DQA MHC class II gene in voles
            (Arvicolinae).
           . Bryja et al., 2007: Density-related changes in selection pattern for major
             histocompatibility complex genes in fluctuating populations of voles.
           . Deter et al., 2008: Association between the DQA MHC class II gene and
             Puumala virus infection in Myodes glareolus, the bank vole.
           . Tollenaere et al., 2008: Multiple parasites mediate balancing selection at two
             MHC class II genes in the fossorial water vole: insights from multivariate analyses
             and population genetics.

   - Generic Wiki article on MHC are also provided for convenience.

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Keywords: balanced selection /  contemporary and historical selection scalesgeneMHC (Major Histocompatibility Complex)phylogeographypopulationpopulation geneticsrodentselectionun-localized /  vole /  ,

Access to generic themes covered: biological objectbio-process-mechanismdiscipline or approachlocationtaxontime range

Navigation suggestion:Evolutionary systematics and biogeography of gerbils from Morocco (134)  
Source:Cosson, J.F. (2008)Mise en évidence de la sélection au gène majeur d'histo-compatibilité chez le campagnol terrestre: quelques méthodes directes et indirectes de détection de la sélection. Conference at the meeting of the "Génétique" network, INRA-EFPA, Arcachon, France, 28 jan. 2008.
Knowledge: no 023 , type: expertise , posted: 2008-09-04 , proposed by:Cosson, Jean-François (INRA-CBGP)

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