I: Identification of immunogenetic factors mediating rodent susceptibility to hantaviruses - SimMasto.org

Identification of immunogenetic factors mediating rodent susceptibility to hantaviruses
a candidate gene approach

This file deals with the following question : 
                      - Is it possible to identify factors mediating genetic susceptibility of rodents to
                        hantaviruses
                      - by studying the genes involved in the immune response
                      - using phylogeny, phylogeography and population genetics ?

The documents below provide three levels of information on rodents' susceptibility to hantaviruses, namely :

[Article]       1.- A bibliographic review on hantavirus-induced immune responses in
                    rodent reservoir (to help determine candidate genes)         
[Slideshow]     2.- A candidate gene approach applied over the macro-evolutive scale(between species) : 
                    the case of integrins.                       
                3.- A candidate gene approach applied over the micro-evolutive scale (within species):
                    the case of Mhc genes and Myodes glareolus at various scales :
[Article]                   a) Experimental infection.
[Article]                   b) 'Local' scale in Jura - France  
[Slideshow]                 c) Regional scale in Europe

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(note: click on the icon opens within the frame, click on the text opens in full window)article  (note: click on the icon opens within the frame, click on the text opens in full window)article  (note: click on the icon opens within the frame, click on the text opens in full window)article  (note: click on the icon opens within the frame, click on the text opens in full window)slideshow  (note: click on the icon opens within the frame, click on the text opens in full window)slideshow 
Keywords: Bunyaviridae /  candidate genecontemporary and historical selection scalesCricetidaeDNA /  Dqa gene /  Drb gene /  Europegene /  genetic resistance and tolerance /  hantavirus /  immune response /  immunogenetics /  integrin receptor gene /  Jura (France) /  local scale /  macro-evolution /  MHC (Major Histocompatibility Complex) /  micro-evolution /  molecular epidemiology /  multiscale /  MuridaeMurinae /  Myodes glareolus /  phylogenyphylogeographypopulationpopulation geneticsregional scaleRNASouth-East Asiaspeciesvirus /  worldwide /  ,

Access to generic themes covered: biological objectbio-process-mechanismconceptdiscipline or approachgeographical rangelocationtaxontaxonomic leveltime rangetool

Navigation suggestion:Community ecology of rodents in sahelian agro-ecosystems (116)  
Source:Charbonnel, N. (2009)file set provided for the 'Centre d'Informations' SimMasto
Knowledge: no 031 , type: expertise , posted: 2010-03-24 , proposed by:Charbonnel, Nathalie (INRA-CBGP)

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